Problems About Scale-Up

Production Scale Up of Nanofibers: A Review

“It’s About the Idea Hitting the Bull’s Eye”: How Aid Effectiveness Can Catalyse the Scale-up of Health Innovations

Background Since the global economic crisis, a harsher economic climate and global commitments to address the problems of global health and poverty have led to increased donor interest to fund effective health innovations that offer value for money. Simultaneously, further aid effectiveness is being sought through encouraging governments in low- and middle-income countries (LMICs) to strengthen...

A Scale-up Design Procedure for Rotating Biological Contactors

A scale-up design procedure, based on a new physical mass transfer (PMT) model, whichdescribes the performance, for aerobic rotating biological contactors (RBC’s) is developed. This scale-up procedure can be used to determine the disc surface area needed to prevent an oxygen limitation or to obtain a specific degree of treatment. In contrast to the empirical, and most previous RBC performance m...

Scale-up Strategies for Membrane-Based Desalination Processes: A Review

Membrane-based technologies have increasingly been chosen in desalination processes, which is evidenced by the increase of large-scale plants constructed in recent years. Indeed, several appropriate strategies should be considered to minimize problems faced during the construction, such as membrane system designs, area requirement, energy requirement, operation and maintenance, and environmenta...

Bioreactor Scale-up for Water-Gas Shift Reaction

A scale-up study has been performed with three different size reactors to establish the optimum operating conditions for the hydrogen production from synthesis gas by biological water-gas shift reaction using the photosynthetic bacterium Rhodosprilliunt rubrum. Optimum medium composition and operating conditions previously determined in a bench scale 1.25 L continuous stirred tank reactor (CSTR...